MOTS-c

Research Peptide for Mitochondrial Signaling, Energy Metabolism and Cellular Stress Response
MOTS-c, short for Mitochondrial Open Reading Frame of the 12S rRNA-c, is an experimental peptide encoded within mitochondrial DNA. It is studied in preclinical research for its potential role in mitochondrial signaling, energy metabolism, glucose regulation and cellular adaptation to metabolic stress.
Since its discovery, MOTS-c has been investigated in laboratory models focused on the relationship between mitochondria, cellular energy balance and homeostasis.
Research Areas of MOTS-c
Mitochondrial function
MOTS-c is used in studies related to mitochondrial activity, energy production and intracellular signaling pathways.
Metabolic regulation
The peptide is investigated in relation to glucose handling, energy balance and metabolic adaptation within preclinical models.
Cellular stress response
MOTS-c is relevant for research into how cells respond to metabolic stress and changing energy demands.
Mitochondrial signaling
In vitro and preclinical studies use MOTS-c to further analyze mitochondrial communication and related signaling pathways.
Cell biology research
The peptide may be used in studies involving cellular homeostasis, metabolic flexibility and adaptive processes at the cellular level.
High purity
MOTS-c 10 mg is supplied as a research compound with ≥99% purity, when confirmed by a batch-specific COA.
How Does MOTS-c Work?
MOTS-c is a mitochondria-derived peptide that may be involved in several metabolic and cellular signaling pathways. In laboratory research, MOTS-c is studied for its influence on processes such as energy balance, glucose-related pathways, mitochondrial activity and cellular stress response.
The activity of MOTS-c is studied exclusively in in vitro, animal model and other preclinical research settings. This product is not intended for human use.
Preparation and Storage
MOTS-c is supplied as a lyophilized powder. For laboratory research, the peptide may be reconstituted with a suitable solvent according to the applicable research protocol.
Store the product dry, protected from light and refrigerated. After reconstitution, storage between 2°C and 8°C is recommended, unless the specific research protocol or batch documentation states otherwise.
Purity and Quality
Each batch of MOTS-c should be verified for identity and purity through a batch-specific Certificate of Analysis. Depending on the testing performed, the COA may include information on purity, peptide content and relevant quality parameters.
Claims regarding heavy metals, endotoxins or microbiological contamination only apply when these tests are specifically listed on the batch-specific COA.
Legal Disclaimer
MOTS-c is intended strictly for laboratory research and preclinical use. This product is not intended for human consumption, medical use, diagnostic use, therapeutic treatment or cosmetic application.
All information regarding MOTS-c is based on laboratory research and preclinical studies. No medical claims are made. Use only in accordance with applicable laboratory safety standards.
Learn More
Read our in-depth blog about MOTS-c, mitochondrial signaling and metabolic research for more background information about this peptide and its research context.